Monday, April 28, 2008

What is the metabolic link between diabetes mellitus and arteriosclerosis

What is the metabolic link between diabetes mellitus and arteriosclerosis?

Diabetes - 4 Answers
Random Answers, Critics, Comments, Opinions :

1 :
High blood glucose from diabetes is destructive to smaller blood vessels. Cellular erosion of the tunica interna of the coronary arteries leads to plaque formation as arteriosclerosis.
2 :
being a diabetic you have to watch your sugar intake and lose weight and excercise ask your docter if your high clolestrol is high and if so take recommened pills for it Lipitor/advicor/zocor/vytorin is good and push yourself away from the table you are what you eat and too much fatty fooods will clog up your ateries and cause plague build up and less blood get to the veins leading to the heart and the heart turns a purperish color which not at all healty yellowish plague build when it is too much you will get arteriosclerosis and it make your heart stop.You might need to start taking plavix or 80mg.of bayer asprin until you see your doctor.
3 :
There is a discussion on the significance of the hyperglycemia in the arteriosclerosis crisis. In intervention test which examined the effect of the glycemic control on the progress of the diabetes mellitus (DM) complication by the pharmacotherapy, by the result of recent prospective study, that hyperglycemia itself is a risk of the arteriosclerosis clarified, and the depression effect of ischemic heart disease by good glycemic control did not reach level of significance. In the meantime, the data in which the after meals hyperglycemia brings about the increase in the ischemic heart disease is shown, and the arteriosclerosis facilitation of the after meals hyperglycemia is indicated. As a metabolism change that it originates from the hyperglycemia and can contribute to the vascular complication, there are enhancement, last saccharification reactant (AGE), activation of protein kinase C, enhancement of the hexosamine route of the polyol route. Diabetes Mellitus combines various lipoprotein metabolism abnormality, and it is also closely related to the crisis of the arteriosclerosis. As a representative change, there are increase of the serum triglyceride value and lowering of HDL - coefficient of aqueous outflow. The significance of lipoprotein metabolism abnormality in the arteriosclerosis of DM is clear, even if the depression effect of cardiovascular event of DM by the hypolipidemic drug therapy is observed. It comes, and changing disease developing mechanism is also gradually being clarified in respect of lipoprotein metabolism abnormality with insulin resistance. Though it had perfectly and not yet clarified one true colors of the insulin resistance, the understanding of the insulin resistance also rapidly advanced, because that the receptor of the thiazolidines which is the insulin resistance drug is PPAR.GAMMA. is clarified.
4 :
Poor diet.

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