Wednesday, December 8, 2010

Can anyone name at least one disease or disorder that animal testing has been vital in developing treatment


Can anyone name at least one disease or disorder that animal testing has been vital in developing treatment?
I know of one but I know nothing about it Diabetes Mellitus. If anyone could help that would be great. Thank you so much!
Medicine - 2 Answers
Random Answers, Critics, Comments, Opinions :
1 :
Diabetes is one, as well as a number of cardiovascular diseases, obesity, the metabolic syndrome, etc. All of these conditions are related to poor fitness and sedentary lifestyle. Animal models have been used to characterize, using advanced molecular and cellular biology techniques, the influence of exercise on the prevention and treatment of these diseases for many years. Studies are also conducted using human subjects. There are many advantages and disadvantages of using both humans and animals for research on physical activity and disease prevention. Can you think of some? This will probably help in writing your essay or whatever it is you need this answer for! In general, experiments using animals are needed to study biological mechanisms at a level that may not be possible in humans because the techniques are too invasive (e.g., removal of a rat's heart after an exercise program can tell us a lot about the effect of that exercise on the heart's cells, but we can't really do this in a human!).
2 :
Many cancers, but CML is a good example in which a breakthrough in treatment, the development of Glivec, involved animal testing. The drug was developed using purified proteins, then cultured cells, then animal testing, and finally remarkable human clinical trials in which virtually everyone went into remission.






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