Wednesday, May 20, 2009

If you can't prevent Diabetes Mellitus can it be genetically diagnosed


If you can't prevent Diabetes Mellitus can it be genetically diagnosed?
Only the complications can be prevented, I was told. The syrup-drink test is not what I'm referring to with my question. Dave, my pet peeve is jerks like you who don't know if there is a gene or not and use scientific research to support your warped obsessions. Is there a gene or not???
Diabetes - 2 Answers
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1 :
One of my pet peeves on this forum is the number of people who say that diabetes is all genetics. They say there is nothing you can do about. You can eat anything you want, it doesn't matter. Then they sign as an authority. Twenty-'leven years diabetic. retired doctor, or some such. It is all BS. The American Diabetes Association mentions genetics, but then says "...people who live in areas that have not become Westernized tend not to get type 2 diabetes, no matter how high their genetic risk." In other words if you don't eat the western diet, you won't get T2 diabetes. The U of Calif has a video on You Tube that explains the why of the current epidemics of obesity and T2 diabetes. Dr. Lustig says that our genetic pool hasn't changed in the past thirty years, but our diet surely has. High fructose corn syrup (HFCS) was introduced in the 1970's, and its use has skyrocketed until it is now the number one source of calories in the US. Doctor Richard Johnson, U of Colorado, explains his work that show the cause of obesity, fatty liver disease, high blood pressure, high triglycerides and diabetes. Please watch the two videos. You'll know more than "twenty-'leven years".
2 :
Well I often say that this is a potentially dangerous forum in which to seek healthcare information and suggesting that you go to YouTube for answers seems a bit of a stretch to say the least. The genetics of type 1 diabetes is known and yes it is possible to test for the presence of such genes. Physicians tend not to do so because if you have the requisite genes we do not know what the likelihood of developing diabetes would be. So if you knew that you had the genetic markers it would induce anxiety but it would not educate you in any meaningful way. In twin studies if one twin develops type 1 diabetes then there is a 50% probability that the other twin will as well. Again this does not mean that if you were tested and that if you were found to have the gene that your likelihood would be 50%. Type 1 diabetes in addition to this gene requires a viral infection - most any will do - and an autoimmune response that destroys the beta (insulin producing) cells of the pancreas. The genetics of type 2 diabetes is stronger than that of type 1 but no specific genes have been found. Type 2 diabetes is thought to be polygenetic (multiple genes) with incomplete penetrance (the genes may be 'turned on' or 'turned off' to varying degrees). To answer your question the genes of type 1 diabetes are known but the presence of these genes by itself does not mean that an individual will develop type 1 diabetes. The genetics of type 2 diabetes is more complex and no specific genes have yet been identified. So far as your comment regarding complications - prompt diagnosis and decisive treatment of both type 1 and type 2 diabetes does reduce the likelihood of developing complications but even perfect diabetic control does not necesarily prevent such complications. If I may be of further assistance please let me know. I wish you the very best of health and in all things may God bless.






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