Saturday, December 12, 2009

What happens to lipid matebolism in starvation and diabetes mellitus


what happens to lipid matebolism in starvation and diabetes mellitus?
biochemistry-lipids
Chemistry - 3 Answers
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3 :
1. I n starvation, there is a decrease in the synthesis of one of the fatty acid synthesizing enzymes called "acetyl-CoA carboxylase" and therefore a decrease in the synthesis of lipids. The starving person breaks down lipids for use as an energy source. 2. In diabetes, t here is an increase in the fatty acid synthesizing enzyme (acetly Co A carboxylase) and an increase in fatty acid synthesis. The circulating blood glucose is not used for energy and the increase lipid synthesis is metabolized instead. The body acts as though it is starving in diabetics. The end result for both the diabetic and the person who is starving is a condition that is known as "ketoacidosis" which is an accumulation of keton bodies in the blood stream. This is a rather simple explanation of lipid metabolism, without using reaction pathways, which can get quite complicated. Hope this answers your question.







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