Tuesday, July 28, 2009

Diabetes mellitus and insipidus...


diabetes mellitus and insipidus...?
what should the pH of urine be for a person who has diabetes mellitus and diabetes insipidus?
Diabetes - 3 Answers
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1 :
Type 2 diabetes is a risk factor for nephrolithiasis in general and has been associated with uric acid stones in particular. The purpose of this study was to identify the metabolic features that place patients with type 2 diabetes at increased risk for uric acid nephrolithiasis. Three groups of individuals were recruited for this outpatient study: Patients who have type 2 diabetes and are not stone formers (n = 24), patients who do not have diabetes and are uric acid stone formers (UASF; n = 8), and normal volunteers (NV; n = 59). Participants provided a fasting blood sample and a single 24-h urine collection for stone risk analysis. Twenty-four-hour urine volume and total uric acid did not differ among the three groups. Patients with type 2 diabetes and UASF had lower 24-h urine pH than NV. Urine pH inversely correlated with both body weight and 24-h urine sulfate in all groups. Urine pH remained significantly lower in patients with type 2 diabetes and UASF than NV after adjustment for weight and urine sulfate (P < 0.01). For a given urine sulfate, urine net acid excretion tended to be higher in patients with type 2 diabetes versus NV. With increasing urine sulfate, NV and patients with type 2 diabetes had a similar rise in urine ammonium, whereas in UASF, ammonium excretion remained unchanged. The main risk factor for uric acid nephrolithiasis in patients with type 2 diabetes is a low urine pH. Higher body mass and increased acid intake can contribute to but cannot entirely account for the lower urine pH in patients with type 2 diabetes. For both avg. PH 6
2 :
Trying to explain what diabetes insipidus is can be challenging enough, without having it confused with "the other diabetes"-sugar diabetes (diabetes mellitus). Both share the word "diabetes" in the name, and both involve thirst and frequent urination, although in DI, urination is more frequent and in much greater volumes than the more common sugar diabetes, and the urine is subsequently extremely dilute and a very pale yellow color or almost clear. But beyond that, there's not much else in common. Some people with DI refer to their condition as either "central DI" or "nephrogenic DI" (depending on what's applicable), because it avoids the confusion caused when people not familiar with DI hear the word diabetes. The more you know about both diabetes insipidus and diabetes mellitus, the better able you are to explain your condition to others-from family members to primary care physicians or emergency technicians. A good starting place is to know the meaning of the words themselves. Diabetes is derived from the Greek verb diabainein, which means to stand with legs apart, as in urination. Diabetes mellitus means, literally, honey-sweet urine (back when doctors would sometimes actually taste people's urine to make a diagnosis). Diabetes insipidus means bland or insipid urine. There are four forms of DI: central DI (also referred to as pituitary or neurogenic DI), nephrogenic DI, gestational DI and dipsogenic DI. DI is caused by the lack of the antidiuretic hormone (vasopressin) or the kidney's inability to respond to this hormone. Sugar diabetes, or diabetes mellitus, comes in two different forms: adult-onset diabetes and insulin-dependent diabetes. Sugar diabetes is caused by lack of the hormone insulin. Not only are DI and sugar diabetes separate conditions, but the diagnostic tests and treatments are different, as well.
3 :
it should not be to low .because if it is low then urine will become acidic and stones can form i should know the number but it has left my head






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Posted by Diabetes Melitus at 2:11 PM