Monday, September 1, 2008

What metabolic similarities are there between diabetes mellitus and prolonged starvation

What metabolic similarities are there between diabetes mellitus and prolonged starvation?

Medicine - 4 Answers
Random Answers, Critics, Comments, Opinions :
1 :
Cells are "hungry" in both cases. The main difference is that in diabetes cells are hungry while there's more than enough food around them. Besides that... I have diagrams and I'm sorry cuz can't present them to you. Most similar to prolonged starving is diabetic ketonic acidosis. Their similarities are: - enhanced lipolysis an beta-oxydation of free fat acids - which leads to ketonic acidosis - enhanced gluconeogenesis And differences: diabetic ketonic acidosis - hyperglycemia, hyperinsulinemia, glucoseuria, hyposodia, polyuria, increased hematocrit, hypovolemia, tachycardia, increased potassium in blood, Kussmaul's breathing, brain uses glucose. prolonged starvation - hypoglycemia, hypoinsulinemia, hyperglucagonemia, protein catabolism, decreased production of albumin in liver, lowering of oncotic pressure, brain uses ketones. I suppose metabolism in hyperosmolar syndrome in d.m. is similar. Sorry for poor English but it's hard to translate scientific terms from one language to another. For marmar: That is correct but only for D.M. type 1. In type 2 insuline receptors on tissue cells aren't sensitive enough and that's why glucose can't enter cell. Type 2 d.m. has increased amount of insulin in the blood.
2 :
a urine dip may show ketones.
3 :
simply D.M. can't make use of the glucose in their body due to the lack of insulin WHILE prolonged starvation they have ran out of glucose because they used it all.
4 :
Feeling hungry..

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